Portable MPM Will Change How Doctors Diagnose Breast Cancer

Michael Giacomelli, PhD, Research Scientist at the Massachusetts Institute of Technology, and his laboratory team have developed a portable system for multiphoton imaging (portable MPM) of large tissue samples within an operating surgical suite. “The system enables true 10x/20x/40x imaging at video rates using VH&E rendering to produce virtual histology images in real-time.”

The technology is currently being tested in breast cancer surgeries, since many lumpectomies result in second surgeries to remove more tissue after histology from the first surgery is complete. With imaging taking place during surgery, these subsequent reoperations may be reduced significantly. Currently, doctors at Memorial Sloan Kettering are considering the tool and/or technique for skin cancer and prostate cancer as well.

Read more about this imaging experiment by clicking here.

Complete removal of cancerous tissue during surgery for breast cancer is essential.  Unfortunately, about 1 in 3 women undergoing lumpectomy for breast cancer will require more than one surgery due to inadequate surgical resection.   Multiphoton microscopy (MPM) can be used to perform video-rate imaging of tissue during surgery to evaluate pathology, ensuring complete removal of cancerous tissue.  I have developed MPM systems enabling very wide area imaging of tissue specimens with real-time rendering using H&E-like appearance (“virtual H&E”).

For more on X-Rays, make sure to check out our article on how medical students utilize them:

No one expects a radiology expert at the level of a medical student. However, if you have at least some knowledge about the basic workings of radiology, especially the chest X-ray, then your understanding sets you apart and allows you to investigate further into the clinical management of a patient.

Whether is it in the critical care setting or the routine humdrum of the emergency room, chest X-rays are one of the most common diagnostic tests ordered by the physician.

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