Fighting Allergies Without Injections?

Where I live in Texas it’s cedar season, which means it’s allergy season. Texas is notorious for its large number of pollen-producing plants including ash, mountain cedar, ragweed, grass and oak… the list goes on and on. When pollination comes around each year, it seems like everyone is coughing, sneezing and congested, with an itchy throat and watery eyes.



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To cope with allergies, I’ve heard some pretty creative (though NOT doctor recommended nor evidence-based) solutions including sleeping with a wet washcloth over the face, eating “local” honey to expose the body to pollens or drinking apple cider vinegar. With my friends going to such extremes to fight allergies, you can imagine how excited I was to see a new paper in JAMA reporting on a 3-year study of sublingual immunotherapy for grass pollen allergy sufferers.



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Sublingual immunotherapy is being explored as an alternative to injection therapies (or subcutaneous immunotherapy), where small amounts of allergens are injected into patients over the course of months and years to build immunity and prevent the allergic reaction. Allergy shots have been used for nearly 100 years and evidence shows that they are highly effective, especially against many pollen species. It is also more cost-effective than simply treating allergic symptoms. With sublingual immunotherapy, instead of injections, the patient takes either a drop solution or tablet under the tongue for one or two minutes and then swallows it.



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Unfortunately, this story has a sad ending. While other studies have claimed to find effectiveness for sublingual immunotherapy in reducing asthma symptoms, this particular study determined that for moderate- severe seasonal allergic rhinitis from grass pollens, 2 years of sublingual therapy was no more effective than the placebo.


In the meantime, we can hope for more studies on the efficacy of facial hair as allergen filters and keep in mind that a severe allergy to pollen can make you more susceptible to anaphylaxis.


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Laurie Breen

Laurie Breen is a freelance writer well-versed in research communications and grant writing. She received her Bachelors Degree in Psychology from Smith College and has worked previously at the University of Queensland's Centre for Clinical Research in Brisbane, Australia. Her favorite conversational topic is "antibiotic-resistant bacteria," making her a big hit at parties.