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The Doctor's Channel

Take a bite from the adults' table. The Doctor’s Channel is the world’s leading video site for physicians. Get the latest news in clinical medicine, disease resource centers, CME programs, and Doc Life, all in under 3 mins or less.

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Pig DNA is Considered Identical to Human DNA

Scientists at Recombinetics are conducting research on pigs in an effort to accelerate cancer cure development and potentially create a sustainable source of genetically-matched human organs for transplantation. While experiments involving farm animals are nothing new in the world of medical research, the pigs at Recombinetics farm in Minnesota are unique because they have been modified to express human traits using TALENs technology. Cancer has been cured in mice models many times, but the same techniques do not seem to translate well in humans. The company believes the 98% similarity between the human genome and the pig genome may help close the gap between successful cures in animal models and resulting efficacious treatments and/or cures for humans. Click here to read more about this company’s research on CNBC. Earlier this year, researchers were able to identify that DNA Bacteria can store information, like hard drives: Researchers at Harvard Medical School have used the CRISPR gene-editing tool to encode five frames of a vintage motion picture into the DNA Bacteria of E. coli bacteria. By reducing each frame into a series of single-color pixels and matching each color to a DNA code, the scientists were able to string together DNA strands that represented the video frames. Non-biological information has been encoded into DNA before, going back as far as 2003. However, this is the first time living organisms have been used as the message’s vessel. Living...

A New ‘Cancer Pen’ Can Help Detect Tumors

In an effort to reduce the risk of re-operation in surgeries for the removal of cancerous tissue, scientists have been developing tools to bring fast and accurate tissue analysis directly to the operating room. A few weeks ago, our Video of the Week featured the work of an MIT research team that’s built a portable multiphoton microscope that can be employed during surgery with the same goal. Michael Giacomelli, PhD, Research Scientist at the Massachusetts Institute of Technology, and his laboratory team have developed a portable system for multiphoton imaging (portable MPM) of large tissue samples within an operating surgical suite. “The system enables true 10x/20x/40x imaging at video rates using VH&E rendering to produce virtual histology images in real-time.” The technology is currently being tested in breast cancer surgeries, since many lumpectomies result in second surgeries to remove more tissue after histology from the first surgery is complete. With imaging taking place during surgery, these subsequent reoperations may be reduced significantly. Currently, doctors at Memorial Sloan Kettering are considering the tool and/or technique for skin cancer and prostate cancer as well. Researchers at the University of Texas have now developed a ‘cancer pen’ that is connected to a mass spectrometer that can comfortably reside in an operating suite. The MasSpec Pen, when pressed against the tissue in question, releases a droplet of water that collects some elements of the contacted tissue, and is then sucked back into the device...

The Future Prescription Drugs Being Developed Right Now

At any one time, there are hundreds of drugs being developed around the world. Some of them could change the way we treat conditions such as lung cancer and asthma. Here are six drugs currently in development that have a real chance of finding their way onto shelves. Drugs are a very touchy subject for aspiring doctors — medical students have definitely taken the time to learn about prescription drugs. The pharmaceutical industry forms a big portion of the affairs that physicians carry out everyday. From the drugs prescribed to the clinical trials conducted, medicine is closely intermingled with the development and use of new medications. However, issues arise when the reporting on the safety, efficacy, and utility of these drugs remains undisclosed due to certain conventional procedures. If you are a medical student who has gone through clinical rotations, you might likely have had this experience (especially on the surgical floors). If you are just starting medical school, it’s something to look forward to! Medical students must also keep cognizant of the opioid epidemic. All it took was one-hundred words to kill over hundreds of thousands of Americans. A new report from the New England Journal of Medicine tells the story of how this short doctor’s note helped facilitate today’s American opioid epidemic. Read more about it here. Since opioids were not widely used forty years ago, so doctors did not have...

What Can Nurses Do That Doctors Can’t?

Patients are increasingly turning to nurse practitioners instead of physicians for a number of reasons. For one thing, they may be more accessible since physicians’ offices are sometimes overcrowded and an appointment is hard to come by. It can also help lower the cost of medical treatments since nurses don’t bill out as high as doctors do. Mostly it’s because people are coming to realize that nurse practitioners are extremely capable and knowledgeable health professionals that can offer a high level of excellent care. In fact, because of their background in nursing, some even say that nurse practitioners have a unique ability to make stronger connections with their patients. As more nurse practitioners open their own practices or become more commonplace in medical facilities, the big question that’s been on the mind of those in the medical community is if nurses can actually replace doctors. There is no simple answer, but there’s no doubt that nurse practitioners are certainly making an impact in the healthcare world. Take a look at how nurse practitioners compare with doctors, and why in some cases, their services might be interchangeable. What can nurse practitioners do NPs have to go well beyond the education and training of a regular RN in order to practice at that advanced level. For starters, you must complete a master’s or doctoral degree program, and then complete advanced practice...

We’re One Step Closer To Identifying Parkinson’s Disease

Researchers at RMIT University in Melbourne, Australia have devised a diagnostic tool for identifying Parkinson’s disease (PD) in patients who may not yet display any motor symptoms. The importance of such a tool lies in the fact that by the time motor symptoms appear, there is usually already irreversible damage to brain tissues. Dinesh Kumar, PhD, the chief investigator on the study, says “many treatment options for Parkinson’s only prove effective when the disease was diagnosed early.“ The team at RMIT built custom software that analyzes a patient’s spiral-drawing style via pen, paper, and a digital drawing tablet. Although the team admits to some limitations within their initial studies, the 93% accuracy rate of early PD diagnosis is spurring additional research and hope for achieving a reliable diagnostic method for identifying PD early. We’ve come a long way to identifying Parkinson’s disease. Earlier this year, researchers have developed an instrument that can identify seventeen diseases, including Parkinson’s. A new instrument has recently been developed to diagnose disease in a non-invasive, cost effective manner. Based on the idea of the breathalyzers used to identify and quantify alcohol consumption, this device would allow for specific programmable disease detection in still healthy individuals. Volatile organic compounds are chemicals that are expressed by the body when pathologic processes occur. Currently, seventeen diseases can be identified with breath analysis with an accuracy of eighty-six percent. Researchers were able to...

Cows Might Be The Future For HIV Vaccines

Until recently, no one has identified an immunogen capable of eliciting broadly neutralizing antibodies (Bnabs) for HIV vaccines in either human or animal models. However, a 2017 National Institute of Allergy and Infectious Diseases (NIAID) research initiative has immunized four cows with the soluble cleaved trimer BG505 SOSIP in an attempt to produce these Bnabs – and has succeeded. Since antibodies in cows are approximately 4 to 5 times longer than typical human antibodies, the cows antibodies have a greater chance of penetrating the sugars surrounding the HIV virus and neutralizing it. There is not yet a clear path to achieving the same results in humans, but according to the director of vaccine research at the NIAID, John Mascola, MD, while the study “doesn’t tell us how to make a vaccine for HIV in human patients […] it does tell us how the virus evades the human immune response.” How far have we come from HIV Vaccinations? It has been a long road in the battle against HIV/AIDS since the epidemic began in the early 1980s. However, in 2013, the virus hit what was widely referred to as a tipping point when, for the first time, more people were newly being treated with antiretroviral drugs than became newly infected with HIV. Despite this milestone, there are still 35 million people estimated to be living with HIV today — 19 million who are estimated to be unaware of their HIV-positive status — and 2 million more people are being infected each year....

Be Wary of Exotic Diseases During Your Medical Elective Placement Overseas

As a heads up for medical students seeking elective placement abroad, be ready to treat patients with exotic diseases. These can be found in poor rural places that were neglected by healthcare services with the worst surroundings in the world. For a hotbed of unimaginable diseases, the health radar is directed towards Southern Sudan. Situated in northeast Africa, the country was divided into Northern Sudan and Southern Sudan by the civil war in 1955. The economy of Northern Sudan is at par with its developed neighbors. However, the south has been ignored and considered underdeveloped even by African standards. According to a health specialist at the World Bank, Francois Decaillet, said, “This really is the forgotten front line when it comes to health.” Malaria, diarrhea, malnutrition, and respiratory infections are the highest killers in most of Africa. Double the count of afflicted persons and you will know the health condition in Southern Sudan. Aside from these, the country is saddled with the existence of horrifying exotic diseases that were exterminated in most of the world. Are you freaked out? Don’t be because GEP’s destination countries were assessed and safety checks are in place to ensure that medical students are out of harm’s way. In case a sufferer with an exotic disease checks in for treatment, you will be shadowed by our local medical partners. If you get goose bumps,...

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